Depression: Different Manifestations

By Zuzanna Myszko

Even though depression is seen as a single disorder, it can be characterized by a myriad of different symptoms. Two people who have both been diagnosed with depression may display completely contrasting feelings and behavior. In response, psychologists must attempt to tailor treatments to properly deal with the patient’s particular manifestation of depression.

People with depression are usually described as experiencing:

  • Sadness
  • Worthlessness
  • Fatigue

However, someone might outwardly display signs of aggression and anxiety while experiencing depression, which changes his or her therapeutic needs. Additionally, this brings up the issue of proper diagnosis. Clinicians must utilize interviews and standardized tests in order to determine the kind of symptoms the patient is experiencing, how many symptoms he or she has, and how long they have been present. These assessments also help the clinician see the extent to which the symptoms are impeding the patient’s day-to-day functioning, which is very important for treatment.

Some forms of diagnosis include:

  • DSM-5
  • Hamilton Depression Rating Scale (HAM-D)
  • Patient Health Questionnaire-9 (PHQ-9)

Tracking symptoms becomes important for the clinician to be able to accurately treat the patient. Usually, it becomes a process of trial and error, especially if medication is involved. However, the more accurate the tracking, the more pinpointed the treatment is because symptoms can be tackled individually. Neuroscientists and other mental health researchers are continuing to attempt to determine the underlying biochemistry of depression in order to eliminate some of the trial and error in treatment.


If you or someone you know is experiencing depression or depressive symptoms, speak with one of our licensed professional psychologists, psychiatrists, psychiatric nurse practitioners, and psychotherapists. Contact us at our Paramus, NJ or Manhattan, NY offices at (201) 368-3700 or (212) 722-1920 respectively to set up an appointment. For more information, visit



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