Antidepressants

By: Lauren Hernandez

            If you or someone you know has been seeing a psychiatrist or psychiatric nurse practitioner for treatment of depression, there are various types of antidepressants a mental health provider can prescribe. It is important to be familiar with different types of antidepressants in order for you, as the patient, to understand what the medication actually does on a neurological level.

The most common type of antidepressant prescribed is a Selective Serotonin Reuptake Inhibitor, known as an SSRI. SSRIs mainly treat depression but they are also effective in the treatment of anxiety disorders, Obsessive-Compulsive Disorders, and Post Traumatic Stress Disorder. Serotonin is a neurotransmitter in the brain which impacts your mood, sexual desire, appetite, sleep, memory and learning as well as other similar functions. On a neurological level, SSRIs prevent serotonin reabsorption which builds up serotonin in the synapse. This allows receptors to receive the signal and react with the optimal amount of serotonin. People suffering from major depressive disorder and anxiety disorders typically have lower serotonin levels. By preventing reabsorption in the synapse via medications, symptoms of these disorders may decrease. In 1987 Prozac was the first approved for treatment of those with depression and became one of the most prescribed antidepressants. Other common SSRIs include Lexapro, Paxil, Zoloft, and Celexa.

Serotonin and norepinephrine reuptake inhibitors, SNRIs differ from SSRIs in that they block the reabsorption of serotonin and norepinephrine. Norepinephrine is a neurotransmitter that influences hormones and the “fight or flight” response in the brain. Approved SNRIs include Cymbalta, Pristiq and Effexor XR.

Some of the other common types of antidepressants prescribed include norepinephrine and dopamine reuptake inhibitors (NDRIs) which block the reabsorption of norepinephrine and dopamine. This is only seen to be effective in the medication bupropion, which is also known as Wellbutrin. Other types of antidepressants that are less common include Tetracyclics (TCA’s), Monoamine Oxidase Inhibitors (MAOI’s), and Serotonin Antagonist and Reuptake Inhibitors. These older medications are not prescribed as frequently because of the development of newer medications that effectively decrease symptoms and have fewer side effects.

Medication is helpful; however, it is most effective when used in combination with different types of psychotherapy or support groups. If you or someone you know is struggling with depression or any type of anxiety or mood disorder, it is important to seek professional help from a psychiatrist or psychiatric nurse practitioner who can provide antidepressants as well as support through talk therapy. If you or someone you know is currently taking antidepressants, it is extremely important to continue taking the medication and avoid discontinuations.

If you or a loved one is suffering from depression, anxiety, or a mood disorder, please contact Arista Counseling & Psychotherapy, located in New York and New Jersey to speak to licensed professional psychologists, psychiatrists, psychiatric nurse practitioners or psychotherapists. To contact the office in Paramus NJ, call (201) 368-3700. To contact the office in Manhattan, call (212) 722-1920. For more information, please visit http://www.counselingpsychotherapynjny.com/ .

Sources:

https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970

https://www.webmd.com/depression/how-different-antidepressants-work#1-3

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